Table 1. Demographic data for study participants stratified by cancer history and hormonal contraceptive use.
Data presented per subject. Subjects with recent exposure to hormonal contraception during at least one visit were classified as hormonal contraceptive users. Demographic characteristics were compared using the Student's t test, Wilcoxon rank-sum test, and Kruskal-Wallis one-way analysis of variance for continuous variables and Pearson's Chi-squared test and Fisher's exact test for categorical variables.
Cancer Survivors | Healthy Controls | Four way group comparison | |||||
---|---|---|---|---|---|---|---|
Subject Characteristics | HC Users (n=42) | HC Non-users (n=84) | P value | HC Users (n=8) | HC Non-users (n=115) | P value | P value |
Age at enrollment (years) φ | 23 (20,27) (16-35) | 25 (20,31) (15-39) | 0.19 | 28.5 (25.5,30) (21-34) | 26 (22,29) (14-39) | 0.219 | 0.075 |
Visits per subject, φ | 2 (1,3) (1-8) | 1 (1,3) (1-6) | 0.411 | 2 (1,3) (1-6) | 1 (1,3) (1-6) | 0.093 | 0.316 |
Length of follow-up (years) φ | 1.2 (0,3.1) (0-7.4) | 1 (0,2.6) (0-6.2) | 0.434 | 2 (0.5,4.0) (0-4.9) | 1 (0,2.5) (0-5.5) | 0.163 | 0.471 |
BMI at enrollment (kg/m2) φ | 22.6 (19.4,24.4) (16.8-34.7) | 23.7 (21.4,25.7) (15.2-50.6) | 0.036 | 22.2 (20.0,27.9) (19.6-43.9) | 23.3 (21.2,26.7) (16.4-54.3) | 0.704 | 0.117 |
Caucasian Race, n (%) | 41 (97.6%) | 76 (90.5%) | 0.267 | 6 (75.0%) | 92 (80.0%) | 0.664 | 0.008 |
Smoking at enrollment, n (%) | 2 (4.8%) | 3 (3.6%) | 1 | 0 (0.0%) | 13 (11.5%) | 0.597 | 0.186 |
Nulligravid, n (%) | 33 (78.6%) | 53 (63.9%) | 0.094 | 5 (62.5%) | 80 (69.6%) | 0.702 | 0.37 |
First visit conducted during early follicular phase, n (%) | 78.60% | 89.30% | 0.105 | 100% | 100% | 1 | <0.001 |
=Results reported as median, interquartile range, and range