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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Fertil Steril. 2014 Jul 10;102(3):838–846.e2. doi: 10.1016/j.fertnstert.2014.05.044

Figure 1. GnRH stimulation of inositol phosphate (IP) accumulation by wild type (WT), V134G, and Y283H mutant GnRHR.

Figure 1

COS-7 cells were transiently transfected with WT, V134G, or Y283H GnRHR as indicated. GnRH-stimulated IP accumulation was measured following stimulation with increasing concentrations of GnRH. Data points represent the mean ± SEM of triplicate samples and are presented as the percentage of the maximum response. *, P<0.05; ***, P<0.001 compared to WT GnRHR. The results shown are from a representative of three independent experiments.