Table 5. Hazard ratio for colorectal cancer incidence for analysis of coffee consumption, stratified by sex and BMI status.

Coffee consumption	Men									Women
	BMI < 18.5			18.5 ≤ BMI < 25.0			25.0 ≤ BMI			BMI < 18.5			18.5 ≤ BMI < 25.0			25.0 ≤ BMI
	Number of cases	HRa	P value	Number of cases	HRa	P value	Number of cases	HRa	P value	Number of cases	HRa	P value	Number of cases	HRa	P value	Number of cases	HRa	P value
For colon cancer incidence
<1 cup/day	6	1.00		177	1.00		48	1.00		16	1.00		163			57	1.00
1 cup/day	3	3.34	0.10	33	1.06	0.75	8	1.04	0.93	2	0.73	0.68	31	0.97	0.86	11	1.25	0.52
2–3 cups/day	6	5.06	0.01	38	1.14	0.48	10	1.05	0.89	2	0.89	0.88	14	0.64	0.12	8	1.35	0.45
≥4 cups/day	2	5.88	0.05	8	1.64	0.18	3	1.92	0.29	0			4	2.12	0.15	0
P for trend			0.01			0.20			0.48			0.69			0.49			0.59
For rectum cancer incidence
<1 cup/day	6	1.00		99			25	1.00		5	1.00		52	1.00		16	1.00
1 cup/day	1	1.49	0.72	23	1.43	0.13	2	0.42	0.25	1	1.42	0.77	11	0.82	1.08	1	0.49	0.50
2–3 cups/day	1	0.76	0.81	25	1.43	0.13	3	0.46	0.22	1	1.83	0.60	11	0.31	1.42	5	3.34	0.04
≥4 cups/day	0			5	1.94	0.16	0			0			0			0
P for trend			0.74			0.06			0.11			0.62			0.61			0.08
For colorectal cancer incidence
<1 cup/day	12	1.00		276	1.00		73	1.00		21	1.00		215	1.00		73	1.00
1 cup/day	4	2.40	0.14	56	1.19	0.24	10	0.82	0.56	3	0.80	0.72	42	0.99	0.97	12	1.11	0.74
2–3 cups/day	7	2.86	0.04	63	1.25	0.13	13	0.82	0.54	3	1.07	0.92	25	0.84	0.42	13	1.79	0.07
≥4 cups/day	2	3.64	0.12	13	1.74	0.06	3	1.13	0.84	0			4	1.51	0.42	0
P for trend			0.03			0.03			0.73			0.87			0.75			0.16

BMI, body mass index; HR, hazard ratio.

^aHazard ratio was adjusted for age, smoking, drinking, family history of colorectal cancer, education, walking time, and regular meat consumption.