Table 6. Hazard ratio for colorectal cancer incidence for analysis of coffee consumption, stratified by sex and meat consumption status.

Coffee consumption	Men									Women
	Low meat consumption			Middle meat consumption			High meat consumption			Low meat consumption			Middle consumption			High meat consumption
	Number of cases	HRa	P value	Number of cases	HRa	P value	Number of cases	HRa	P value	Number of cases	HRa	P value	Number of cases	HRa	P value	Number of cases	HRa	P value
For colon cancer incidence
<1 cup/day	75	1.00		69	1.00		35	1.00		70	1.00		67			50	1.00
1 cup/day	14	1.12	0.71	12	0.77	0.41	12	1.64	0.15	10	1.01	0.97	16	1.00	0.99	11	0.99	0.98
2–3 cups/day	17	1.25	0.42	18	0.91	0.72	13	2.01	0.04	5	0.82	0.67	7	0.63	0.25	11	1.17	0.65
≥4 cups/day	2	1.03	0.97	5	1.53	0.37	4	2.98	0.05	3	7.19	0.00	1	1.76	0.58	1	0.74	0.77
P for trend			0.51			0.79			0.01			0.25			0.41			0.82
For rectum cancer incidence
<1 cup/day	46	1.00		40	1.00		24	1.00		29	1.00		17	1.00		12	1.00
1 cup/day	6	0.79	0.60	10	1.221	0.58	8	1.90	0.12	6	1.239	0.64	5	1.119	0.83	2	0.71	0.66
2–3 cups/day	7	0.88	0.77	12	1.122	0.74	8	1.94	0.13	3	0.872	0.83	7	1.905	0.18	2	0.89	0.89
≥4 cups/day	3	2.51	0.14	1	0.599	0.62	1	1.25	0.83	0			0			0
P for trend			0.54			0.99			0.22			0.68			0.31			0.61
For colorectal cancer incidence
<1 cup/day	121	1.00		109	1.00		59	1.00		99	1.00		84	1.00		62	1.00
1 cup/day	20	1.00	0.99	22	0.93	0.77	20	1.78	0.03	16	1.08	0.78	21	1.02	0.92	13	0.96	0.89
2–3 cups/day	24	1.12	0.62	30	0.98	0.94	21	1.98	0.01	8	0.85	0.66	14	0.94	0.83	13	1.14	0.69
≥4 cups/day	5	1.59	0.32	6	1.21	0.65	5	2.36	0.08	3	3.89	0.03	1	1.12	0.91	1	0.58	0.60
P for trend			0.36			0.84			0.01			0.49			0.89			0.96

HR, hazard ratio.

^aHazard ratio was adjusted for age, smoking, drinking, family history of colorectal cancer, education, body mass index, and walking time.