Table 7. Hazard ratio for colorectal cancer incidence for analysis of coffee consumption, stratified by sex and age.
| Coffee consumption | Men | Women | ||||||||||
| 40–59 years | 60–79 years | 40–59 years | 60–79 years | |||||||||
| Number of cases |
HRa |
P value |
Number of cases |
HRa |
P value |
Number of cases |
HRa |
P value |
Number of cases |
HRa |
P value |
|
| For colon cancer incidence | ||||||||||||
| <1 cup/day | 103 | 1.00 | 137 | 1.00 | 75 | 1.00 | 179 | 1.00 | ||||
| 1 cup/day | 22 | 0.91 | 0.70 | 22 | 1.11 | 0.65 | 20 | 0.91 | 0.72 | 26 | 0.91 | 0.64 |
| 2–3 cups/day | 31 | 0.86 | 0.46 | 27 | 1.52 | 0.05 | 14 | 0.63 | 0.12 | 13 | 0.81 | 0.48 |
| ≥4 cups/day | 9 | 1.24 | 0.55 | 4 | 1.73 | 0.28 | 3 | 0.98 | 0.98 | 2 | 2.80 | 0.15 |
| P for trend | 0.89 | 0.03 | 0.21 | 0.84 | ||||||||
| For rectum cancer incidence | ||||||||||||
| <1 cup/day | 52 | 1.00 | 87 | 1.00 | 30 | 1.00 | 52 | 1.00 | ||||
| 1 cup/day | 18 | 1.57 | 0.10 | 10 | 0.82 | 0.55 | 7 | 0.93 | 0.87 | 6 | 0.74 | 0.49 |
| 2–3 cups/day | 21 | 1.27 | 0.37 | 9 | 0.81 | 0.54 | 11 | 1.51 | 0.26 | 6 | 1.38 | 0.46 |
| ≥4 cups/day | 4 | 1.30 | 0.62 | 1 | 0.73 | 0.75 | 0 | 0.00 | 0.99 | 0 | 0.00 | 0.99 |
| P for trend | 0.41 | 0.47 | 0.62 | 0.68 | ||||||||
| For colorectal cancer incidence | ||||||||||||
| <1 cup/day | 155 | 1.00 | 224 | 1.00 | 105 | 1.00 | 231 | 1.00 | ||||
| 1 cup/day | 40 | 1.13 | 0.50 | 32 | 1.00 | 1.00 | 27 | 0.92 | 0.69 | 32 | 0.87 | 0.47 |
| 2–3 cups/day | 52 | 0.99 | 0.95 | 36 | 1.24 | 0.24 | 25 | 0.86 | 0.51 | 19 | 0.94 | 0.78 |
| ≥4 cups/day | 13 | 1.27 | 0.42 | 5 | 1.36 | 0.50 | 3 | 0.76 | 0.64 | 2 | 2.25 | 0.26 |
| P for trend | 0.70 | 0.19 | 0.44 | 0.98 | ||||||||
HR, hazard ratio.
aHazard ratio was adjusted for smoking, drinking, family history of colorectal cancer, education, body mass index, walking time, and regular meat consumption.