Table 1.
Physical characteristics of male and female LCR and HCR rats.
| F-LCR | M-LCR | F-HCR | M-HCR | Interaction | Strain | Sex | |
|---|---|---|---|---|---|---|---|
| Distance run (m) | 336.5 ± 52.9 | 252.3 ± 42.7 | 1974.1 ± 108.6 | 1624.5 ± 112.1 | 0.0001 | <0.0001 | <0.0001 |
| Work (J) | 176.7 ± 30.9 | 219.8 ± 43.9 | 853.1 ± 53.9 | 1019.6 ± 93.7 | 0.0074 | <0.0001 | <0.0001 |
| Body weight (g) | 255.4 ± 27.2 | 460.4 ± 40.4 | 203.0 ± 16.7 | 334.4 ± 35.8 | 0.0025 | <0.0001 | <0.0001 |
| Soleus weight (mg) | 111.4 ± 12.8 | 157.3 ± 32.5 | 116.3 ± 10.1 | 162.5 ± 23.3 | NS | NS | <0.0001 |
| EDL weight (mg) | 109.5 ± 9.2 | 176.1 ± 17.4 | 107.3 ± 17.6 | 171.3 ± 19.9 | NS | NS | <0.0001 |
| Red gastrocnemius weight (mg) | 521.1 ± 56.2 | 732.9 ± 96.6 | 480.3 ± 80.6 | 600.4 ± 164.2 | NS | 0.0299 | <0.0001 |
| Tibialis anterior weight (mg) | 452.1 ± 50.3 | 693.3 ± 86.9 | 478.0 ± 79.9 | 633.3 ± 105.6 | NS | NS | <0.0001 |
| Heart weight (mg) | 789.4 ± 76.4 | 1229.6 ± 119.7 | 707.9 ± 44.3 | 1090.3 ± 100.1 | NS | 0.0016 | <0.0001 |
Data are displayed as mean ± SD (n = 5, in each group). Two-factor analysis of variance was used to calculate P values and determine statistically significant interactions and main effects for strain (HCR vs LCR) and sex (male vs female). EDL = extensor digitorum longus, F-HCR = female high-capacity runner, M-LCR = male low-capacity runner.