Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Palmitoylation-defective plakophilin-2 disrupts the localization of endogenous desmosomal components. A431 cells expressing wild-type plakophilin-2 (Pkp-2 WT; A–C, G–I and M–O) or plakophilin-2 C603S (Pkp-2 C603S; D–F, J–L and P–R) were grown on glass coverslips, fixed and immunostained using antibodies recognizing the Myc epitope tag (A,D), desmocollin-2 (Dsc-2; G,J) and desmoglein-2 (Dsg-2; M,P). Desmoplakin (DP) colocalization is shown in panels B, E, H, K, N and Q. Scale bar: 10 µm.
