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. 2014 Aug 1;2:121–130. doi: 10.7150/jgen.8833

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Volcano plots contrasting gene expression in clusters of samples. Each plot indicates the significance on the y-axis (negative log P) against the magnitude differential expression on the log2 scale. Each gene is indicated by a circle, and the q-value 5% FDR cutoff is indicated by the horizontal line at NLP 2.64 for the comparisons of the craniosynostosis clusters in (A) through (C). Plot (D) contrasts normal and all craniosynostosis samples, and is drawn to a different scale since the differentiation of some genes is much stronger.