Table 4. Genes in the pathways of interest.

Cluster 1	Human disease	Gene
hsa04260	Cardiac muscle contraction	ATP1A1, ATP1B3, ATP2A2, CACNA2D4, COX4I1, COX5A, COX5B, COX6B1, COX6C, COX7A2, COX7A2L, COX7B, COX7C, COX8A, CYC1, SLC9A6, TPM4, UQCR10, UQCR11, UQCRC1, UQCRC2
hsa05010	Alzheimer's disease	ADAM10, ADAM17, APH1A, APP, ATP2A2, ATP5A1, ATP5B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5H, ATP5J, ATP5O, BID, CALM1, CALM2, CALM3, CAPN1, CAPN2, CASP3, CDK5, CHP, COX4I1, COX5A, COX5B, COX6B1, COX6C, COX7A2, COX7A2L, COX7B, COX7C, COX8A, CYC1, FADD, FAS, GNAQ, HSD17B10, IL1B, LPL, LRP1, MAPK3, NAE1, NCSTN, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFB10, NDUFB11, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB7, NDUFB8, NDUFC1, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS7, NDUFS8, PLCB3, PPP3CB, PPP3R1, PSEN1, PSENEN, SDHB, TNF, TNFRSF1A, UQCR10, UQCR11, UQCRC1, UQCRC2
hsa00190	Oxidative phosphorylation	ATP5A1, ATP5B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5H, ATP5I, ATP5J, ATP5J2, ATP5L, ATP5O, ATP6AP1, ATP6V0B, ATP6V0D1, ATP6V0E1, ATP6V1A, ATP6V1B2, ATP6V1C1, ATP6V1D, ATP6V1E1, ATP6V1G1, COX17, COX4I1, COX5A, COX5B, COX6B1, COX6C, COX7A2, COX7A2L, COX7B, COX7C, COX8A, CYC1, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFB10, NDUFB11, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB7, NDUFB8, NDUFC1, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS7, NDUFS8, PPA1, SDHB, TCIRG1, UQCR10, UQCR11, UQCRC1, UQCRC2
hsa05012	Parkinson's disease	SEPT5, ATP5A1, ATP5B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5H, ATP5J, ATP5O, CASP3, COX4I1, COX5A, COX5B, COX6B1, COX6C, COX7A2, COX7A2L, COX7B, COX7C, COX8A, CYC1, HTRA2, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFB10, NDUFB11, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB7, NDUFB8, NDUFC1, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS7, NDUFS8, PARK7, SDHB, SLC18A2, SLC25A5, UBA7, UBE2G1, UBE2J1, UBE2J2, UBE2L6, UQCR10, UQCR11, UQCRC1, UQCRC2, VDAC3
hsa05016	Huntington's disease	AP2S1, ATP5A1, ATP5B, ATP5C1, ATP5D, ATP5E, ATP5F1, ATP5G2, ATP5G3, ATP5H, ATP5J, ATP5O, CASP3, CLTB, CLTC, COX4I1, COX5A, COX5B, COX6B1, COX6C, COX7A2, COX7A2L, COX7B, COX7C, COX8A, CYC1, DCTN1, DCTN2, DCTN4, DLG4, DNAL4, GNAQ, HDAC2, NDUFA1, NDUFA2, NDUFA3, NDUFA4, NDUFA5, NDUFA6, NDUFA7, NDUFA8, NDUFA9, NDUFB10, NDUFB11, NDUFB2, NDUFB3, NDUFB4, NDUFB5, NDUFB7, NDUFB8, NDUFC1, NDUFS1, NDUFS2, NDUFS3, NDUFS4, NDUFS5, NDUFS7, NDUFS8, PLCB3, POLR2B, POLR2E, POLR2H, POLR2K, POLR2L, PPARG, REST, SDHB, SLC25A5, SOD1, UCP1, UQCR10, UQCR11, UQCRC1, UQCRC2, VDAC3
Cluster 2	Metabolism	Gene
hsa00140	Steroid hormone biosynthesis	COMT, CYP1B1, HSD17B12, HSD17B7, SRD5A1, SRD5A3, UGT2A1, UGT2B15
hsa00980	Metabolism of xenobiotics by cytochrome P450	ADH5, LDH3B1, CYP1B1, CYP2E1, GSTK1, GSTM5, GSTP1, MGST1, MGST2, MGST3, UGT2A1, UGT2B15
hsa00380	Tryptophan metabolism	ACAT1, ACAT2, AFMID, CYP1B1, ECHS1, GCDH, HADHA, MAOA, MAOB, OGDH, TPH1, WARS
Cluster 3	Genetic information processing	Gene
hsa03010	Ribosome	FAU, RPL10, RPL10A, RPL11, RPL12, RPL15, RPL17, RPL18, RPL19, RPL23, RPL24, RPL26, RPL27, RPL28, RPL29, RPL3, RPL30, RPL31, RPL34, RPL35, RPL35A, RPL36AL, RPL37A, RPL38, RPL4, RPL41, RPL5, RPL7A, RPL8, RPLP0, RPLP1, RPLP2, RPS11, RPS13, RPS15, RPS15A, RPS16, RPS20, RPS23, RPS24, RPS25, RPS27L, RPS4X, RPS4Y1, RPS5, RPS6, RPS7, RPS9, RSL24D1, UBA52