Scheme 2. Multiple sequence alignment of six MTTases.
Two from RimO_(E. coli K-12 and T. maritima DSMZ3109), two from MiaB (E. coli K- 12 and T. maritima DSMZ3109), one from MtaB (B. subtilis MGNA-001), and one from e-MtaB (M. musculus). The alignment was performed with ClustalW at the EBI site. Totally conserved residues are indicated by stars, and conserved cysteine residues are indicated by arrows. The three domains UPF0004, Radical-SAM, and TRAM are shown on the right.