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. 2014 Jul 1;111(5):944–954. doi: 10.1038/bjc.2014.355

Table 2. Relationship between p62 and LC3B expression and clinicopathologic variables in OSCCs.

 
 
p62 in cytoplasm
 
p62 in nucleus
 
LC3B
 
Variable No. of cases Low High P-value Low High P-value Low High P-value
Age
⩽50 Years 71 38 33 0.882 41 30 0.243 39 32 0.735
>50 Years
124
65
59
 
82
42
 
65
59
 
Sex
Male 187 97 90 0.285a 118 69 1.000a 97 90 0.001a*
Female
8
6
2
 
5
3
 
7
1
 
T stage
T1/T2 126 71 55 0.182 79 47 0.882 68 58 0.81
T3/T4
69
32
37
 
44
25
 
36
33
 
N stage
N0 145 86 59 0.002* 88 57 0.239 82 63 0.125
N1/N2/N3
50
17
33
 
35
15
 
22
28
 
M stage
M0 192 103 89 0.103a 120 72 0.298a 102 90 1.000a
M1
3
0
3
 
3
0
 
2
1
 
Stage
I/II 106 66 40 0.004* 63 43 0.25 60 46 0.318
III/IV
89
37
52
 
60
29
 
44
45
 
Histologic grade
G1/G2 168 101 67 <0.001* 101 67 0.033* 92 76 0.319
G3
27
2
25
 
22
5
 
12
15
 
Lymphovascular invasion
Absent 147 87 60 0.002* 90 57 0.348 85 62 0.028*
Present
48
16
32
 
33
15
 
19
29
 
Necrosis
Limited/no 145 86 59 0.002* 89 56 0.403 82 63 0.125
Extensive 50 17 33   34 16   22 28  

Abbreviation: OSCC=oral squamous cell carcinoma.

*P<0.05.

a

Fisher exact test.