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. 2014 Sep 1;6:225. doi: 10.3389/fnagi.2014.00225

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Copyright © 2014 Jasien, Daimon, Wang, Shapiro, Martin and Maudsley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protein expression in wild type and BTBR mouse hippocampus. Western blotting was performed using mouse hippocampal protein lysates (A). Protein levels were measured in BTBR and control mice with respect to the following proteins in the hippocampus: pro-BDNF (B), mature BDNF (C), phospho-TrkB (D), total TrkB (E), Akt (F) phospho-synapsin 1 (G), synapsin 1 (H) synaptophysin (I), PSD95 (J), spinophilin (K), Neuronal cell marker NeuN (L). Data are expressed as means ± s.e.m. Asterisks represent p-values as shown: ^*p < 0.05, ^**p < 0.01. Statistical significance was measured using a Student's t-test, n = 3 for each group.