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. 2014 Sep 1;6:225. doi: 10.3389/fnagi.2014.00225

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Copyright © 2014 Jasien, Daimon, Wang, Shapiro, Martin and Maudsley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Signaling pathway analysis of cortical and hippocampal proteins differentially regulated BTBR and WT. Cortical and hippocampal proteins exhibiting differential regulation between BTBR and control mice were analyzed for potential functional pathway interactions using KEGG (A-cortex, B-hippocampus) and Ingenuity Canonical Signaling pathway analysis (C-cortex, D-hippocampus). For (A,B), the top 10 most significantly-populated (calculated with Hybrid scores: enrichment factor (R) ^* (−log₁₀ enrichment probability, P) neuronally-specific KEGG or Canonical signaling pathways are shown.