Table 1.
The Genotype and Allelic Distributions of the FokI Polymorphism of the VDR Gene in Intervertebral Disc Degeneration Patients and Controls
| Genotypes | Alleles | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| SNP VDR | Population studied | n | n (%) | n (%) | n (%) | n (%) | n (%) | p | OR (95% CI) | HWE |
| TT | TC | CC | T | C | ||||||
| FokI | DD patients | 121 | 54 (44.6) | 50 (41.4) | 17 (14.0) | 158 (65.3) | 84 (34.7) | 0.025 | 1.58 (1.07–2.32) | 0.624 |
| rs2228570 | Controls | 131 | 75 (57.2) | 46 (35.2) | 10 (7.6) | 196 (74.8) | 66 (25.2) | 0.737 | ||
CI, confidence interval; HWE, Hardy–Weinberg equilibrium; IDD, intervertebral disc degeneration; OR, odds ratio; SNP, single-nucleotide polymorphism.