Table 3.
Variable definition | Endometriosis | Primary dysmenorrhea |
Time effect P value |
Time ∗ group effect P value |
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---|---|---|---|---|---|---|---|---|---|---|
Baseline | Week 4 | Week 8 | Week 12 | Baseline | Week 4 | Week 8 | Week 12 | |||
Pain in VAS a | 6.6 ± 2.1 | 5.8 ± 2.5 | 5.2 ± 2.4 | 5.4 ± 2.3 | 6.3 ± 1.9 | 5.0 ± 2.8 | 4.6 ± 2.8 | 4.4 ± 2.7 | 0.000∗ | 0.698 |
| ||||||||||
Menstrual duration | 2.9 ± 0.8 | 2.9 ± 0.8 | 2.9 ± 0.8 | 2.7 ± 0.8 | 2.7 ± 0.6 | 2.6 ± 0.7 | 2.6 ± 0.7 | 2.6 ± 0.7 | 0.250 | 0.779 |
Blood volume | 36.4 ± 38.8 | 31.4 ± 32.4 | 30.7 ± 31.4 | 28.9 ± 31.2 | 26.1 ± 22.0 | 22.4 ± 16.6 | 18.0 ± 12.0 | 19.8 ± 14.8 | 0.001∗ | 0.760 |
Duration of pain | 2.2 ± 1.0 | 2.3 ± 1.1 | 1.9 ± 1.0 | 2.1 ± 1.1 | 2.2 ± 0.9 | 2.0 ± 1.2 | 1.8 ± 1.1 | 1.8 ± 1.2 | 0.017∗ | 0.520 |
Use of painkillers | 1.9 ± 3.7 | 1.7 ± 3.4 | 1.7 ± 3.3 | 1.9 ± 4.1 | 0.5 ± 1.1 | 0.5 ± 1.1 | 0.5 ± 0.9 | 0.4 ± 1.1 | 0.783 | 0.791 |
| ||||||||||
WHOQOL-BREF scoreb | ||||||||||
Global | 11.1 ± 2.2 | 11.4 ± 2.3 | 11.5 ± 2.6 | 12.2 ± 2.0 | 11.8 ± 3.1 | 11.7 ± 3.0 | 11.7 ± 3.0 | 11.9 ± 3.1 | 0.046∗ | 0.208 |
Physiological domain | 13.0 ± 2.0 | 12.6 ± 2.1 | 12.5 ± 2.3 | 12.8 ± 2.0 | 13.3 ± 2.2 | 13.5 ± 2.4 | 13.4 ± 2.1 | 13.7 ± 2.6 | 0.303 | 0.348 |
Psychological domain | 12.8 ± 2.1 | 12.4 ± 2.1 | 12.2 ± 2.0 | 12.6 ± 2.0 | 13.1 ± 2.7 | 12.9 ± 2.3 | 12.7 ± 2.3 | 12.9 ± 2.4 | 0.013∗ | 0.707 |
Social domain | 13.5 ± 1.6 | 13.0 ± 1.8 | 12.8 ± 1.7 | 13.0 ± 1.8 | 14.1 ± 1.9 | 13.7 ± 2.0 | 13.6 ± 2.1 | 13.7 ± 1.9 | 0.002∗ | 0.883 |
Environmental domain | 13.9 ± 1.6 | 13.6 ± 1.8 | 13.3 ± 1.9 | 13.5 ± 1.9 | 14.3 ± 2.1 | 14.1 ± 2.2 | 13.6 ± 2.2 | 13.6 ± 2.2 | 0.000∗ | 0.698 |
aVAS refers to the Visual Analogue Scale; bWHOQOL-BREF refers to the World Health Organization Quality of Life-brief version. Data presented with mean ± standard deviation; data adjusted for age. ∗Significance at the P < 0.05 level.