TABLE 1.

The clinical features and evolution of the 10 affected members from 3 families

Individual (sex/age, y)	Age of Onset. y	Follow-Up, y	Site of Onset	Cervical Dystonia	Cranial Dystonia	Upper Limb Dystonia	Tremor	Myoclonus
Family 1
I-1 (F/deceased)	27	—	Cervical	Torticollis	Laryngeal dysphonia, adductor dysphonia	—	Head, mild bilateral postural arms
II-1 (M/age 67)	40	27	Cervical	Torticollis to the right	Blepharospasm, adductor dysphonia	—	Head, mild bilateral postural asymmetric arms
II-4 (M/69)	30	39	Laryngeal	Torticollis	Blepharospasm, adductor dysphonia, oromandibular	Mild	Head; mild on the left arm
II-7 (W/deceased)	30	27	Cervical	Torticollis	Adductor dysphonia	—	Head, bilateral postural asymmetric arms
III-7 (W/36)	19	17	Cervical	Torticollis	Adductor dysphonia	Mild	Head
Family 2
III-1 (M/65)	3-4	61	Cervical	Torticollis	Laryngeal, oromandibular, blepharospasm	—	Head, mild bilateral postural asymmetric arms
IV-1 (F/39)	4-5	30	Laryngeal	Torticollis	Laryngeal, oromandibular, blepharospasm	Mild fingers bilateral	Finger tremor and asymmetric arm tremor	Torticollis and retrocollic myoclonic jerks
IV-2 (M/37)	30	7	Right arm	-	-	Mild fingers only on the right	Mild postural tremor, more on the right arm
Family 3
II-1 (F/31)	6	25	Cervical	Torticollis	Laryngeal	Mild	Mild, postural and action, asymmetric arms; head
III-1 (M/9)	6	3	Left arm	No	No	-	Moderate, mainly on action, asymmetric arms	Proximal and distal myoclonic jerks (arms)

F, female; M, male.