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. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Am J Hematol. 2013 Sep 30;89(1):19–24. doi: 10.1002/ajh.23568

A. Relationship between C1D1 AUC_0-∞ and dose levels (P=0.36, Kruskal-Wallis test). B. Relationship between C1D1 Cmax and dose levels (P=0.11, ANOVA). DL1, Dose level 1= 30/30 mg; DL2, dose level 2=30/50 mg; and DL3, dose level 3=50/50 mg. Solid line within the box represents the median, the lower and upper box borders represent the first and third quartiles, and the whiskers extend to the minimum and maximum values. The mean is marked with a triangle.

A. Relationship between C1D1 AUC_0-∞ and dose levels (P=0.36, Kruskal-Wallis test). B. Relationship between C1D1 Cmax and dose levels (P=0.11, ANOVA). DL1, Dose level 1= 30/30 mg; DL2, dose level 2=30/50 mg; and DL3, dose level 3=50/50 mg. Solid line within the box represents the median, the lower and upper box borders represent the first and third quartiles, and the whiskers extend to the minimum and maximum values. The mean is marked with a triangle.