Flavopiridol exposure and response. A. Relationship between best response and C1D1 AUC0-∞. (P=0.04, Kruskal-Wallis test; *P<0.05). B. Relationship between best response and C1D1 Cmax (P=0.16, ANOVA not assuming equal variances). PR, partial response; SD, stable disease; PD, progressive disease. Solid line within the box represents the median, the lower and upper box borders represent the first and third quartiles, and the whiskers extend to the minimum and maximum values. The mean is marked with a triangle.