Table 2.
Univariate analysis of the effect of recipient variables on pediatric renal allograft survival.
| Variable | N (%) of cases | Survival rate |
Log rank P | |
|---|---|---|---|---|
| 5 years | 10 years | |||
| Age, years | ||||
| 5–10 | 60 (22.0) | 0.745 | 0.529 | 0.04 |
| 10–17 | 213 (78.0) | 0.842 | 0.621 | |
| Sex | ||||
| Male | 180 (65.9) | 0.834 | 0.509 | 0.858 |
| Female | 93 (34.1) | 0.727 | 0.569 | |
| Original kidney disease | ||||
| Chronic glomerulonephritis | 56 (20.5) | 0.799 | 0.510 | 0.801 |
| Chronic pyelonephritis | 31 (11.4) | 0.834 | 1.00 | |
| Amyloidosis | 2 (0.7) | 1.800 | 0.675 | |
| Hereditary nephritis | 10 (3.7) | 0.750 | 0.500 | |
| Obstructive uropathy | 18 (6.6) | 0.830 | 0.634 | |
| ESKD | 156 (57.1) | 0.814 | 0.617 | |
| Number of acute rejections | ||||
| None | 115 (42.1) | 0.931 | 0.824 | 0.001 |
| 1 | 69 (25.3) | 0.830 | 0.587 | |
| > 1 | 89 (32.6) | 0.759 | 0.494 | |
| Ischemia intervals, min | ||||
| < 45 | 111 | 0.826 | 0.576 | 0.629 |
| > 45 | 162 | 0.832 | 0.652 | |
| ATN after transplant | ||||
| Yes | 18 (6.6) | 0.677 | 0.271 | 0.002 |
| No | 255 (93.4) | 0.848 | 0.621 | |
| Immunosuppression | ||||
| Azathioprine-based | 13 (4.8) | 0.462 | 0.308 | 0.001 |
| Cyclosporin-based | 26 (9.5) | 0.833 | 0.441 | |
| Triple therapy | 141 (51.6) | 0.833 | 0.628 | |
| Tacrolimus-based | 92 (33.7) | 0.932 | 0.828 | |
| Rapamycin-based | 1 (0.4) | 0.00 | 0.00 | |
| Hypertension | ||||
| No | 132 (48.4) | 0.834 | 0.812 | 0.05 |
| Yes | 141 (51.7) | 0.831 | 0.538 | |
| Transplant received | ||||
| 1st | 270 (98.9) | 0.839 | 0.607 | 0.129 |
| Re-transplant | 3 (1.1) | 0.667 | 0.333 | |