Table 1.
Characteristics of 2,991 FHS and 898 PIVUS participants
| FHS | PIVUS | |||
|---|---|---|---|---|
| Men (n=1,316) | Women (n=1,675) | Men (n=437) | Women (n=450) | |
| Age, years | 59 (10) | 59 (10) | 70 (0.2) | 70 (0.2) |
| Systolic blood pressure, mmHg | 130 (17) | 127 (20) | 146 (22) | 153 (23) |
| Diastolic blood pressure, mmHg | 78 (9) | 74 (9) | 79 (10) | 78 (10) |
| Body-mass index, kg/m2 | 28 (4) | 27 (6) | 27 (4) | 27 (5) |
| Diabetes mellitus, % | 11 | 9 | 12 | 9 |
| Anti-hypertensive treatment, % | 28 | 24 | 29 | 30 |
| Smoker, % | 15 | 16 | 11 | 13 |
| Total cholesterol, mg/dl | 200 (36) | 212 (38) | 200 (37) | 222 (37) |
| HDL cholesterol, mg/dl | 44 (12) | 58 (16) | 54 (14) | 64 (16) |
| GDF-15, ng/L | 1,180 (637) | 1,153 (615) | 1,257 (421) | 1,162 (390) |
| eGFR, ml/min/1.73m2 | 91 (42) | 89 (43) | 84 (21) | 78 (21) |
| NSAID use, % | 9 | 13 | n.a. | n.a. |
Values are mean (standard deviation) unless otherwise indicated.
FHS, Framingham Heart Study; PIVUS, Prospective Investigation of the Vasculature in Uppsala Seniors study; HDL, high-density lipoprotein; GDF-15, growth differentiation factor-15; eGFR, estimated glomerular filtration rate; NSAID, non-steroidal anti-inflammatory drug; n.a., not available