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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Autoimmunity. 2010 Mar;43(2):140–155. doi: 10.3109/08916930903229239

Figure 6.

Figure 6

GpG-ODN and CpG-ODN bind TLR-9 and other TLRs. Mouse TLR stimulation was tested by assessing NF-κB activation in HEK293 cells transfected to express the indicated TLR. CpG-ODN or GpG-ODN was incubated alone or in the presence of the indicated positive control ligand for TLR activation. Data presented are the average of two independent experiments with comparable results. HKLM, heat-killed L. monocytogenes; Poly(I:C), polyinosinic: polycytidylic acid; LPS, E. coli K12 lipopolysaccharide; Flagellin, S. typhimurium flagellin; Loxo, loxoribine; and CpG ODN 1826.