Fig. 5.

Scanning electron micrographs of samples of ibuprofen crystals, physical mixture and melt dispersion powders. (A) Ibc (distinctive geometric shape of crystalline ibuprofen, magnification 500×); (B) Ibsmp₁₀ (ibuprofen crystals are identified in the physical mixture, magnification 500×); (C) Ibsmd₁₀ (magnification 500×) and (D) Ibsmd₁₀ (magnification 1000×) (in Ibsmd₁₀ size of the individual crystallite comprising the agglomerate was significantly decreased than the individual crystal of pure drug).