Table 1.

Echocardiographic characteristics of the animals

	Females			Males
	Sham	Moderate MI	Large MI	Sham	Moderate MI	Large MI
N	7	9	12	8	8	12
BW (g)	232 ± 23*	227 ± 8#	262 ± 22$†	343 ± 56	322 ± 12	300 ± 24‡
IM size (%)	---	32 ± 7	47 ± 6	---	33 ± 9	46 ± 6
LVDA (mm2)	2.5 ± 0.4	4.6 ± 0.8‡	5.4 ± 1‡$†	3.2 ± 0.3	5.3 ± 0.6‡	8.2 ± 0.7$‡
LVSA (mm2)	0.8 ± 0.1	3 ± 0.8‡	3.9 ± 0.9‡$†	1.2 ± 0.1	3.4 ± 0.8‡	5.7 ± 1.1$‡
LVDA/BW (mm2/g)	0.011 ± 0.002	0.020 ± 0.003‡	0.020 ± 0.004‡†	0.010 ± 0.001	0.016 ± 0.002‡	0.027 ± 0.002$‡
LVSA/BW (mm2/g)	0.003 ± 0.0006	0.013 ± 0.003‡	0.015 ± 0.004‡†	0.003 ± 0.0006	0.010 ± 0.002‡	0.019 ± 0.004$‡
FAC (%)	67 ± 2	34 ± 10‡	26 ± 16‡	63 ± 4	36 ± 11‡	29 ± 14‡

BW: body weight; LVDA: left ventricular diastolic area; LVSA: left ventricular systolic area; FAC: fractional area change; MI: myocardial infarction

^*p < 0.05 compared with sham males;

^#p < 0.05 compared with moderate MI males

^†p < 0.05 compared with large MI males;

^‡p < 0.05 compared with the respective sham;

^$p < 0.05 compared with respective moderate MI size.