TABLE 2.
Controls | Paediatric CF | Adult CF
|
||
---|---|---|---|---|
IS | HS | |||
Central MCC % | 36.2 ± 18.0 | 35.2 ± 18.0 | 32.7 ± 13.5 | 45.7 ± 23.7 |
Central DTPA % | 45.4 ± 16.6 | 57.1 ± 20.6 | 56.0 ± 19.0 | 62.8 ± 21.7 |
Central ABS % | 9.2 ± 10.0 | 21.9 ± 5.0** | 23.3 ± 13.0* | 17.1 ± 12.2# |
AACTc | 18.6 ± 9.4 | 14.5 ± 8.8 | 14.3 ± 6.3 | 26.8 ± 10.8## |
AACIn | 25.9 ± 9.6 | 30.6 ± 11.4 | 30.5 ± 10.3 | 38.8 ± 7.7# |
AACABS | 7.3 ± 3.5 | 16.1 ± 7.7** | 16.2 ± 8.8** | 12.0 ± 6.8## |
Data are presented as mean ± SD. CF: cystic fibrosis; IS: isotonic saline; HS: hypertonic saline; MCC: mucociliary clearance; DTPA: diethylene triamine penta-acetic acid; ABS: DTPA absorption; AACTc: area above the technetium-99m–sulfur colloid retention curve; AACIn: area above the 111In-DTPA retention curve; AACABS: area above the ABS curve.
: p<0.05 versus controls;
: p<0.01 versus controls;
: p<0.05 versus adult CF subjects with IS treatment;
: p<0.01 versus adult CF subjects with IS treatment.