Table 2.
Differences in inflammatory markers across 25(OH)D tertiles
| Serum 25(OH)D tertiles | ||||
|---|---|---|---|---|
| Tertile 1 n = 289 (<31.4 nmol/L) |
Tertile 2 n = 287 (≤31.4 < 53.1 nmol/L) |
Tertile 3 n = 291 (≥53.1 nmol/L) |
P a | |
| IL-6 (pg/ml) | 2.04 ± 1.87 | 1.72 ± 1.63 | 1.41 ± 1.21 | <0.001 |
| sIL-6r (ng/mL) | 102.42 ± 49.4 | 98.17 ± 54.08 | 110.09 ± 54.10 | 0.01 |
| sgp130 (ng/mL) | 320.76 ± 60.52 | 315.52 ± 6.76 | 303.61 ± 55.64 | 0.001 |
| CRP (μg/mL) | 3.42 ± 2.56 | 2.98 ± 2.21 | 2.72 ± 2.16 | 0.004 |
| TNF-α (pg/mL) | 5.39 ± 4.31 | 5.00 ± 2.80 | 9.85 ± 87.19 | 0.02 |
| sTNFR1 (pg/mL) | 1,568.92 ± 810.61 | 1,497.77 ± 641.03 | 1,366.13 ± 478.39 | 0.005 |
| sTNFR2 (pg/mL) | 2,894.80 ± 847.46 | 2,773.12 ± 717.88 | 2,632.08 ± 663.02 | <0.001 |
| IL-1ß (pg/mL) | 0.38 ± 2.22 | 0.21 ± 0.73 | 0.40 ± 1.92 | 0.41 |
| IL1ra (pg/mL) | 139.75 ± 67.83 | 145.98 ± 86.30 | 142.46 ± 84.94 | 0.85 |
| IL-10 (pg/mL) | 96.05 ± 381.91 | 66.11 ± 263.97 | 73.48 ± 312.67 | 0.15 |
| IL-18 (pg/mL) | 395.24 ± 159.53 | 405.03 ± 145.45 | 405.77 ± 146.56 | 0.31 |
aThe analysis (age and sex adjusted) by Wilcoxon-Rank-sum test (Kruskal-Wallis test)