Table 4.

Relationship between vitamin D and inflammatory markers

	Model 1a		Model 2b
	β ± SE	P	β ± SE	P
Log (IL-6)	−0.11 ± 0.03	<0.0001	−0.10 ± 0.03	0.0001
Log (sIL6r)	0.11 ± 0.04	0.003	0.11 ± 0.03	0.004
Log (sgp130)	−0.0006 ± 0.0003	0.07	−0.0008 ± 0.0003	0.01
Log (CRP)	−0.04 ± 0.02	0.04	−0.01 ± 0.03	0.07
Log (IL-18)	−0.035 ± 0.06	0.53	−0.01 ± 0.06	0.83

^aParsimonious models obtained by backward selection method from initial models including all covariates reported in the table and age, sex and PTH. PTH parathyroid hormone, CRP C-reactive protein, sIL6r soluble IL-6 receptor, sgp130 signaling-transducing 130-kDa component

^bParsimonious models also adjusted for physical activity, caloric and alcohol intake, season of blood collection, smoking, pack-years, years of cigarette smoking, cortical bone mineral density, ADL disability, CES-D, CHD, creatinine; ADL, Katz’s Index; CES-D Center for Epidemiologic Studies Depression Scale; CHD coronary heart disease