Table 5.
Echocardiographic evaluation of cardiac structural parameters in aging female F344xBN rats (mean ± SEM)
| Groups | 6 months | 26 months | 30 months |
|---|---|---|---|
| IVSs (cm) | 0.193 ± 0.008 | 0.253 ± 0.003* | 0.239 ± 0.013 |
| IVSd (cm) | 0.118 ± 0.012 | 0.151 ± 0.003 | 0.149 ± 0.004 |
| LVIDs (cm) | 0.378 ± 0.017 | 0.331 ± 0.009* | 0.356 ± 0.011 |
| LVIDd (cm) | 0.610 ± 0.022 | 0.593 ± 0.009 | 0.606 ± 0.10 |
| LVPWs (cm) | 0.193 ± 0.002 | 0.267 ± 0.007 | 0.288 ± 0.009* |
| LVPWd (cm) | 0.153 ± 0.010 | 0.166 ± 0.004 | 0.189 ± 0.008* |
| RVDd (cm) | 0.105 ± 0.016 | 0.138 ± 0.009 | 0.111 ± 0.006 |
| LVM (g) | 0.487 ± 0.10 | 0.658 ± 0.09 | 0.646 ± 0.04 |
Six-month-old animals; 26-month-old animals; 30-month-old animals
*p < 0.05, significantly different from 6-month-old animals