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. 2014 Aug 22;46(8):e110. doi: 10.1038/emm.2014.49

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Copyright © 2014 KSBMB.

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Effect of MSC/HGF transplantation on Ito cell activation. (a) α-SMA and desmin were detected by immunohistochemistry in liver sections. Scale bar, 500 μm. (b) Liver extracts from each group were subjected to western blot analysis using antibodies against α-SMA and desmin. (c) The relative amount of α-SMA and desmin proteins was calculated by densitometry. Normal rats, N; control fibrotic animals, S; and fibrotic animals transplanted with MSCs, M, or MSCs/HGF, H. Data represent the mean±s.d. for each group. α-SMA; α-smooth muscle actin (*P<0.05, **P<0.01, ***P<0.005).