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. 2014 Aug 27;14:616. doi: 10.1186/1471-2407-14-616

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© Sun et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Inhibition of miR-1246 reduced migration and invasion of SMMC7721 and BEL7402. (A, B) Transwell migration (n = 4) and invasion (n = 4) assays showed that SMMC7721 cells transfected with the miR-1246 inhibitor (800 nM) had lower invasive and migratory potentials than the control (inhibitor control). (A) is a microscopic image of crystal violet staining; (B) shows the statistical results. (C, D) Transwell migration (n = 4) and invasion (n = 4) assays showed that BEL7402 cells transfected with the miR-1246 inhibitor (800 nM) had lower invasive and migratory potentials than the control (inhibitor control). (C) is a microscopic image of crystal violet staining; (D) shows the statistical results. Data represent the mean ± SD of four independent experiments. *P < 0.01.