Table 2.

Input parameters for the Markov decision-analytic model - base case

Parameter	Base case	SE	Distribution	Reference
RR reduction (%)
Diabetes - men	2.60	0.003	lognormal	[30]
Diabetes - women	2.20	0.002	lognormal	[30]
CHD - men	0.94	0.001	lognormal	[31]
CHD - women	1.14	0.001	lognormal	[31]
Stroke - men	1.20	0.001	lognormal	[32]
Stroke - women	1.70	0.002	lognormal	[33]
Colon cancer - men	1.04	0.001	lognormal	[34]
Colon cancer - women	0.40	0.001	lognormal	[34]
Cost/year data input (€) 1
Diabetes	3,312	331	gamma	[35]
CHD first year	4,386	439	gamma	[36–38]
CHD subsequent years	1,183	118	gamma	[36–38]
Stroke first year	13,319	1,332	gamma	[36]
Stroke subsequent years	4,756	476	gamma	[36]
Colon cancer	9,575	958	gamma	[36]
Intervention cost2	35	3.50	gamma	[15]
Intervention cost3	21	2.13	gamma	[15]
Utilities
At risk	0.71	0.04	beta	[40]
Diabetes	0.63	0.06	beta	[17]
CHD 1	0.47	0.05	beta	[17]
CHD 1+	0.56	0.06	beta	[17]
Stroke 1	0.50	0.05	beta	[17]
Stroke 1+	0.50	0.05	beta	[17]
Colon cancer 1	0.64	0.06	beta	[17]
Colon cancer 1+	0.64	0.06	beta	[17]
Dead	0

RR, relative risk; CHD, coronary heart disease.

¹expressed in the year 2011 euros; ²intervention cost for the years 1,6,11,16.

³intervention cost for the other years.