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Effect of LPS challenge on relative mRNA expression in whole blood cells. Anticoagulated whole blood was collected 24 h post-instillation to PBS or MMA-SS and challenged with LPS (100 ng/ml). Whole blood cells were collected in RNA later 24 h after LPS challenge. The Venn diagram represents genes altered due to LPS challenge, 433 genes overlapped between PBS and MMA-SS treated rats. The figure shows no differential effect of LPS challenge after treatment for Cxcl2 and Tnfa.
