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. 2014 Sep 1;30(7):593–602. doi: 10.1089/jop.2014.0016

FIG. 7.

FIG. 7.

Comparison of expression of thioredoxin (TRx) (A) and thioredoxin reductase (TRxR) (B) in the neural retina of rats exposed to light after 2-week dark adaptation. Comparison of expression of TRx normalized to levels of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) in rats treated with or without the multifunctional JHX-4 or topical Optixcare EH indicates that JHX-4 reduced the induction of TRx to a greater extent than Optixcare EH. Similarly, comparison of the expression of TRxR normalized to levels of GAPDH in rats treated with or without the multifunctional JHX-4 or topical Optixcare EH indicates that both JHX-4 and Optixcare reduced the induction of TRx compared with the levels observed in the untreated rats. The JHX-4 data have been previously published.35 Mean±SD; n=6. An asterisk (*) denotes a significant difference (P<0.05) when compared to the untreated NLD group while the hatched symbol (#) denotes a significant difference (P<0.05) compared to the untreated LD group.