FIG. 9.

Reduction of tear flow induced by twice daily subcutaneous injections of scopolamine in adult Lewis rats topically treated with or without the comfort agents Optixcare, Optixcare with hyaluronic acid, i-Drop hyaluronic acid, and the nutraceutical Optixcare EH. Tear flow in each rat, determined with phenol red thread as the average of both eyes, decreased over time in the untreated rats, and topical administration of either of the comfort agents Optixcare, Optixcare with hyaluronic acid, or i-Drop hyaluronic acid did not alter this decrease. Concomitant treatment with nutraceutical Optixcare EH in similar scopolamine-injected rats appeared to preserve tear flow; n=6 rats.