Table 3. List of the limbic and nociceptive brain regions. The first column lists the name of the system, the second column lists the major regions within each system and the third column lists the corresponding ROIs. The limbic system included the striatum (accumbens, septum and ventral pallidum), amygdala and hippocampus. The nociceptive system included the thalamus, sensorimotor (primary motor and sensory cortices), polymodal regions (insula and cingulate) and the periaqueductal gray.

System	Region	ROIs
Limbic	Striatum	1,2,3,4,77,78,91,92
	Amygdala	5,6
	Hippocampus	45,46,47,48,49,50,51,52,53,54
Nociceptive	Thalamus	85,86,87,88,89,90
	Sensorimotor	25,26,35,36
	Polymodal	15,16,21,22
	Periaqueductal Grey	71,72