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. Author manuscript; available in PMC: 2014 Sep 2.
Published in final edited form as: Lab Invest. 2011 Jun 27;91(10):1480–1490. doi: 10.1038/labinvest.2011.105

Table 3.

Results of MYB break-apart FISH

Xenograft
model		 Passage
# tested		 # intact
probe
pairs		 # separate
green signals
(centromeric
probe)		 # separate
red signals
(telomeric
probe)		 Interpretation
ACCX2 3 2 1 0 Rearrangement of 1 MYB locus with loss of 6p.
Duplication of second intact MYB locus.
ACCX5M1 4 1 1 1 Rearrangement of 1 MYB locus. Retention of one
intact MYB locus.
ACCX6 4 1 1 0 Rearrangement of 1 MYB locus with loss of 6p.
Retention of one intact MYB locus.
ACCX9 4 0 2 1 Duplication of rearranged MYB locus. Loss of
second MYB locus.
ACCX11 2 1 1 0 Rearrangement of 1 MYB locus with loss of 6p.
Retention of one intact MYB locus.
ACCX12 5 1 2 0 Duplication of rearranged MYB locus, with loss of
6p. Retention of one intact MYB locus.
ACCX14 2 1 1 1 Rearrangement of 1 MYB locus. Retention of one
intact MYB locus.
ACCX15 2 1 1 0 Rearrangement of 1 MYB locus with loss of 6p.
Retention of one intact MYB locus.
ACCX16 1 1 1 0 Rearrangement of 1 MYB locus with loss of 6p.
Retention of one intact MYB locus.
ACCX19 1 2 1 0 Rearrangement of 1 MYB locus with loss of 6p.
Duplication of second intact MYB locus.
ACCX20M1 1 1 1 1 Rearrangement of 1 MYB locus. Retention of one
intact MYB locus.
ACCX22 1 2 0 0 Wild-type configuration (2 intact MYB loci).