Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Sep 1;206(5):655–670. doi: 10.1083/jcb.201401070

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Ashrafi et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 8. — Parkin recruitment to damaged axonal mitochondria requires PINK1. (A–D) YFP-Parkin is recruited to mitochondria of PINK1^+/+ (A and B) but not PINK1^−/− (C and D) rat hippocampal axons depolarized with 40 µM Antimycin A (Ant A). White and cyan arrowheads denote YFP-Parkin–positive mitochondria; cyan arrowheads point to mitochondria analyzed with line scans in B and D. Orange and brown arrowheads denote corresponding points in images and line scans. (E) Frequency of Parkin recruitment in the indicated genotypes before and 15 min after Antimycin A treatment. n = 87–101 mitochondria from four microfluidic devices per genotype. *, P < 0.05. Error bars represent means ± SEM. AU, arbitrary unit. Bars, 5 µm.