Figure 9. EC expression of stabilized β-catenin produces a cell-autonomous conversion of choroid plexus ECs from PLVAP⁺Claudin5^– to PLVAP^–Claudin5⁺.

Ctnnb1^flex3/+ Cdh5-IRES-MCreM mice were treated with 200 μg 4HT at P3 and analyzed at P23. Two images are shown per genotype. White arrows point to a few of the several dozen choroid plexus capillary ECs per image that have converted to a PLVAP^–Claudin5⁺ state. Scale bar: 200 μm.