Figure 5. Aneurysm development in ecCNP KO mice.
Images of the aneurysms in male ecCNP KO/ApoE KO mice show dilation of the aortic arch (B) or abdominal aorta (D), loss of vascular smooth muscle and thinning of the vascular wall (B), and degradation of elastin (D) in comparison with WT/ApoE KO animals (A and C). Scale bars: 50 μm. Representative of 4/9 male animals. EVG, elastic van Gieson.