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. 2014 Sep 2;5:203. doi: 10.3389/fphar.2014.00203

FIGURE 6.

FIGURE 6

Good and bad practice examples for steady state of drug induced block by Terfenadine. (A) Bad practice example of an I/t plot showing insufficient steady state of block, which would lead to underestimation of the drug effect. (B) Good practice example where the drug exposure time as well as the number of drug application repeats has been doubled, leading to an acceptable steady state.