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. Author manuscript; available in PMC: 2014 Sep 2.
Published in final edited form as: Eur J Med Chem. 2012 Jun 21;54:647–659. doi: 10.1016/j.ejmech.2012.06.017

Table 1.

The Names, Structures and IC50 Data of Trimethine Cyanine Compounds.

Type of compound Name Structure IC50 (μM)
Group A
Trimethine cyanine compounds containing benzo[c,d]indolium groups in the two ends
11 [MHI-21] graphic file with name nihms619223t1.jpg 4.1 ± 0.1
12 [MHI-06] graphic file with name nihms619223t2.jpg 12.0 ± 0.5
13 [MHI-36] graphic file with name nihms619223t3.jpg 15.5 ± 0.2
Group B
Trimethine cyanine compounds containing indolium groups in the two ends.
22 [E-14] graphic file with name nihms619223t4.jpg 284.2 ± 3.5
23 [E-6] graphic file with name nihms619223t5.jpg 160.8 ± 1.2
24 [E-4] graphic file with name nihms619223t6.jpg 6.3 ± 0.3
28 [A-C3] graphic file with name nihms619223t7.jpg 368.3 ± 25.9
29 [A-N3] graphic file with name nihms619223t8.jpg 291.7 ± 40.1
30 [MHI-106] graphic file with name nihms619223t9.jpg At 100 μM concentration 80% activity retained
31 [MHI-128] graphic file with name nihms619223t10.jpg At 100 μM concentration 95% activity retained
Group C
Trimethine cyanine compounds containing benzo[e]indolium group as the end units
25 [E-5] graphic file with name nihms619223t11.jpg 20.3 ± 0.2
26 [E-18] graphic file with name nihms619223t12.jpg 18.0 ± 0.5
27 [E-8] graphic file with name nihms619223t13.jpg 14.3 ± 0.2