Table 1.
Type of compound | Name | Structure | IC50 (μM) |
---|---|---|---|
Group A Trimethine cyanine compounds containing benzo[c,d]indolium groups in the two ends |
11 [MHI-21] | 4.1 ± 0.1 | |
12 [MHI-06] | 12.0 ± 0.5 | ||
13 [MHI-36] | 15.5 ± 0.2 | ||
Group B Trimethine cyanine compounds containing indolium groups in the two ends. |
22 [E-14] | 284.2 ± 3.5 | |
23 [E-6] | 160.8 ± 1.2 | ||
24 [E-4] | 6.3 ± 0.3 | ||
28 [A-C3] | 368.3 ± 25.9 | ||
29 [A-N3] | 291.7 ± 40.1 | ||
30 [MHI-106] | At 100 μM concentration 80% activity retained | ||
31 [MHI-128] | At 100 μM concentration 95% activity retained | ||
Group C Trimethine cyanine compounds containing benzo[e]indolium group as the end units |
25 [E-5] | 20.3 ± 0.2 | |
26 [E-18] | 18.0 ± 0.5 | ||
27 [E-8] | 14.3 ± 0.2 |