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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Angew Chem Int Ed Engl. 2014 May 19;53(27):7001–7005. doi: 10.1002/anie.201310609

Scheme 2.

Scheme 2

The proposed structures for the ICL products and the proposed major fragmentation pathways for the [M+H]+ ion of dU-1 (A) or dT-1 cross-link (B) observed in LC-MS/MS.