TABLE 5.

Conditional likelihood of cognitive impairment in long lived individuals and their relatives versus spouse controls, adjusted for age, education and study site.

	No. at Risk	Affected N (%)	Mean Age of Cases	Age, Education and Study Site Adjusted Odds Ratio
65–79 years
Sons and Daughters	109	6 (5.5)	69.6 ± 3.6	0.3 (0.1–0.7)
Nieces and Nephews in the Offspring Generation	224	30 (13.4)	71.4.6 ±4.6	1.5 (0.8–2.9)
Spouse Controls	216	28 (13.0)	71.7 ± 4.5	1.0 (reference)
80–95 years
Probands	94	49 (52.2)	91.9 (2.4)	0.8 (0.4–1.8)
Siblings in the Proband Generation	249	120 (48.2)	89.2 (4.2)	1.1 (0.7–1.8)
Spouse Controls	103	45 (43.7)	86.9 ± 3.8	1.0 (reference)