Table 1.

Univariate gonadotropins and subject characteristics associated with sperm suppression to <1 million/mL or azoospermia

Variable	<1 million/mL		Azoospermia
	OR (CI)	p-value	OR (CI)	p-value
All treatment groups, n = 69 (T+NES 0, T+NES 8, T+NES 12)
LH week 0	1.12 (0.36, 3.52)	0.84	0.98 (0.31, 3.1)	0.97
LH week 2	2.81 (1.78, 4.46)	<0.001	2.4 (1.5, 3.6)	<0.001
LH week 4	6.81 (2.98, 15.6)	<0.001	4.4 (2.2, 8.6)	<0.001
LH week 24	5.0 (2.5, 9.95)	<0.001	7.6 (2.7, 21.1)	<0.001
FSH week 0	0.82 (0.32, 2.11)	0.69	0.78 (0.3, 2.0)	0.61
FSH week 2	2.03 (1.34, 3.07)	0.001	1.9 (1.3, 2.9)	0.001
FSH week 4	3.37 (2.01, 5.66)	<0.001	3.1 (1.9, 5.2)	<0.001
FSH week 24	3.47 (2.05, 5.87)	<0.001	3.3 (2.0, 5.6)	<0.001
Age	1.01 (0.97, 1.06)	0.55	1.0 (0.97, 1.1)	0.33
BMI	1.02 (0.88, 1.19)	0.75	1.1 (.91, 1.2)	0.46
Race	2.28 (1.21, 4.31)	0.011	3.1 (142, 6.8)	0.005
Baseline sperm concentration	1.0 (0.99, 1.01)	0.92	1.0 (1.0, 1.0)	0.82
T+NES 0 vs. T + NES 8/12	8.7 (2.7, 27.9)	<0.001	5.8 (1.8, 18.4)	0.003
T+NES8 and T+NES 12 groups only, n = 43
LH week 0	1.10 (0.22, 5.63)	0.91	0.98 (0.31, 3.08)	0.97
LH week 2	2.18 (1.24, 3.83)	0.006	2.36 (1.54, 3.63)	<0.001
LH week 4	27.2 (2.8, 258.4)	0.004	4.36 (2.22, 8.58)	<0.001
LH week 24	3.53 (1.67, 7.43)	0.001	7.58 (2.71, 21.1)	<0.001
FSH week 0	0.71 (0.18, 2.7)	0.61	0.78 (0.30, 2.02)	0.61
FSH week 2	1.5 (0.93, 2.44)	0.10	1.94 (1.29, 2.93)	0.001
FSH week 4	3.22 (1.65, 6.23)	0.001	3.16 (1.88, 5.23)	<0.001
FSH week 24	2.78 (1.51, 5.12)	0.001	3.34 (1.99, 6.13)	<0.001
Age	1.04 (0.97, 1.10)	0.25	1.02 (0.97, 1.07)	0.33
BMI	1.02 (0.83, 1.25)	0.84	1.06 (0.91, 1.23)	0.46
Race	2.07 (101, 4.24)	0.045	2.65 (1.18, 5.93)	0.018
Baseline sperm concentration	1.00 (0.99, 1.01)	0.70	1.0 (0.99, 1.01)	0.82
T+NES 8 vs. T+NES 12	0.45 (0.12, 1.68)	0.23	0.5 (0.45, 1.7)	0.27