Table 3.

Clusters within regions of interest that demonstrated significant changes in activation due to drinking a milkshake among restrained eaters.

	Number of voxels	P-value	Max. z-score	x (mm)	y (mm)	z (mm)
Restrained—Activation greater before milkshake
Fattening>Object
Hypothalamus	2	0.038	2.46	−8	−10	−8
L amygdala	3	0.032	2.72	−24	0	−12
R insula	134	0.040	3.4	36	22	−2
L thalamus	169	0.034	3.48	−20	−18	2
Occipital lobe (BA 18, 19, cuneus, lingual gyrus)	777	0.004	4.43	20	−80	22
Occipital lobe (BA 19)	567	0.014	4.92	−42	−74	18
Non-fattening>Object
None
Fattening>Non-fattening
Brainstem	212	0.035	3.71	0	−42	−50
Brainstem	261	0.023	3.79	−10	−16	−14
Hypothalamus	3	0.036	2.61	8	−6	−12
Hypothalamus	2	0.038	2.85	−8	−10	−8
L amygdala	6	0.042	2.61	−24	−8	−26
R inferior frontal	405	0.009	4.62	36	24	−16
R inferior frontal	246	0.032	4.01	52	14	−2
Medial OFC (BA 10, 32)	189	0.044	3.97	−14	18	−22
R insula	124	0.044	4.26	34	22	−16
L thalamus	289	0.012	3.1	−16	−6	0
R thalamus	294	0.011	3.94	10	−8	4
Occipital lobe (BA 17, 18, 19, cuneus, lingual gyrus)	5603	3.67E-011	4.52	10	−78	−8
Restrained—Activation greater after milkshake
Fattening>Object
None
Non-fattening>Object
Medial OFC (BA 10, 32)	201	0.034	3.55	−10	36	−16
Occipital lobe (BA 17, 18, R BA 19, middle occipital gyrus, lingual gyrus)	2744	1.2E-007	4.67	10	−90	−4
Fattening>Non-fattening
None

OFC=orbitofrontal cortex; BA=Brodmann area; L=left; R=right. Coordinates are in MNI space.