Table 7.
Variation of 3-Substituent in Series 18 Compounds
 | |||
|---|---|---|---|
| compound | R | pEC50 (RE) |
|
| LRH-1 | SF-1 | ||
| 18a | nHex | 6.6 (0.24) | 7.2 (0.78) |
| 18t | H | ia | ia |
| 18u | nBu | 6.7 (0.54) | 7.4 (0.86) |
| 18v | nOct | 5.8 (0.15) | 6.8 (0.67) |
| 18w | SiMe2Ph | 6.8 (0.53) | 7.2 (0.33) |
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