Table 8.
Effect of Variations in Skeleton on Biological Activity
 | ||
|---|---|---|
| compound | pEC50 (RE) |
|
| LRH-1 | SF-1 | |
| 18a | 6.6 (0.24) | 7.2 (0.78) |
| 19 | 6.6 (0.23) | 7.2 (0.42) |
| 20a (RJW103) | 5.9 (0.20) | 6.5 (0.49) |
| 20b | 6.5 (0.13) | ia |
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