. Author manuscript; available in PMC: 2014 Sep 2.

Published in final edited form as: J Perinat Med. 2013 Jan;41(1):27–44. doi: 10.1515/jpm-2012-0272

Table 3.

Results of an indirect patient meta-analysis of randomized clinical trials comparing vaginal progesterone vs. placebo and cerclage vs. expectant management in this population of patients concluded that the efficacy of each intervention is similar

Outcome	Indirect comparison Vaginal progesterone vs Cerclage
Outcome	RR (95% CI)	P value^b
Preterm birth <32 weeks	0.70 (0.33–1.50)	0.88
Preterm birth <28 weeks	0.71 (0.27–1.88)	0.88
Preterm birth <35 weeks	0.88 (0.51–1.52)	0.96
Preterm birth <37 weeks	1.19 (0.82–1.74)	0.94
Perinatal mortality	1.05 (0.30–3.64)	0.98