Table 2.
Characteristics examined for predicting difficult induction onto buprenorphine
| Characteristics | Difficult induction (n = 32) |
Regular induction (n = 537) |
χ2/t | p |
|---|---|---|---|---|
| Female, (%) | 50.0 | 41.8 | 0.834 | .361 |
| Age, mean yrs | 33.3 (SD11.6) | 33.4 (SD10.2) | −0.052 | .959 |
| White race, (%) | 87.5 | 86.4 | 0.032 | .857 |
| Education, mean yrs | 13.3 (SD2.5) | 13.1 (SD2.3) | 0.422 | .673 |
| Never married, (%) | 56.0 | 48.8 | 0.489 | .485 |
| Employed full-time, (%) | 43.8 | 55.5 | 1.682 | .195 |
| Smoker (baseline) (%) | 78.6 | 72.3 | 0.526 | .468 |
| Chronic pain at baseline (%) | 56.2 | 40.8 | 2.973 | .085 |
| Ever used heroin (%) | 30.4 | 20 | 1.308 | .253 |
| Previous treatment for opioid dependence (%) | 21.9 | 33.0 | 1.696 | .193 |
| Past year substance dependence (%) | ||||
| Alcohol | 9.7 | 4.1 | 2.151 | .142 |
| Marijuana | 6.5 | 4.3 | 0.321 | .571 |
| Stimulants | 0.0 | 1.6 | 0.492 | .483 |
| Sedative | 3.2 | 6.6 | 0.565 | .452 |
| Cocaine | 6.5 | 3.3 | 0.849 | .357 |
| BPI Severity Score, mean (Baseline) | 2.7 (SD2.6) | 3.0 (SD2.6) | 0.560 | .576 |
| BPI Interference Score, Mean | 2.7 (SD2.8) | 3.0 (SD2.9) | 0.499 | .618 |
| Pre-induction COWS score, Mean | 10.09 (SD2.30) | 12.77 (SD3.52) | −4.388 | <.001 |
| Post-induction COWS score, Mean | 13.64 (SD2.87) | 5.17 (SD3.52) | 13.330 | <.001 |