Figure 1.

Proposed interactions between basophils, B and T cells in individuals with minimal change nephrotic syndrome (MCNS). The red and black solid lines with arrows represent interactions that have been previously reported, while the red and blue dotted lines with arrows represent interactions that have not been reported in MCNS. The red lines with arrows represent promotional functions and the blue dotted lines with flat heads represent suppressive functions. IL, interleukin; Th, T helper cell; TLR, Toll-like receptor; IFN, interferon; IgE, immunoglobulin E; CIC, circulating immune complexes.