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FXR overexpression inhibits prostate cancer cell proliferation. (A) FXR expression levels were determined by western blot analysis in LNcaP cells transfected with plasmids expressing an empty vector or FXR. (B) BrdU assays were used to determine the cell proliferative potential of LNcaP cells transfected with an empty vector or FXR. A450 absorption was assayed following transfection for 24 h. FXR, farnesoid X receptor; BrdU, bromodeoxyuridine; EV, empty vector.
